(精编)【高血压英文教学精品课件】 Renal disorder in systemic disease.pptVIP

Renal disorder in systemic disease;A huge variety of systemic conditions can affect the function of the kidneys, from acute illnesses to drugs and more insidious illnesses.;;Diabetic nephropathy ;;;;;;Diagnosis ;Investigation ;Management of diabetic nephropathy:;Hypertensive nephropathy/nephrosclerosis ;Hypertension also increases the risk of renal failure through the effects of: Cholesterol embolisation to the kidneys The presence of renal artery stenosis (particularly if bilateral);Most patients present with significant hypertension and/or its complications (e.g. cardiac failure, MI, stroke) or biochemical/clinical evidence of renal failure. There has usually been a history of hypertension for about 10 years, but some patients will present without having had any previous evidence of hypertension.;Management;Vasculitides;Vasculitides that tend to cause renal impairment: ;Sickle cell disease ;Multiple myeloma;Cast nephropathy in a patient with multiple myeloma. Light microscopy picture showing characteristic fractured cast and giant cell reaction (arrows).