(精编)Antibiotics11教学课件.ppt

Antibiotics First known use of antibiotic substances – 600 B.C. – moldy soybean curd Pasteur – 1877 – observed that anthrax bacilli were killed when grown in the presence of other bacteria Fleming – 1929 – antibacterial activity of penicillin discovered Florey and Chain – 1938 – First clinical use of penicillins What is an antibiotic? Definition: A product of metabolism of other organisms A synthetic product that is a structural analogue of a naturally occurring antibiotic Antagonizes the growth or survival of one or more species of microorganisms Effective in low concentrations Soil micr