(精编)RNA干扰与miRNA教学课件.pptVIP

Whole genome sequences indicate ~20,000 genes, ~3x the number in yeast. Differential RNA processing generates proteomic diversity, but why such increased complexity? But, now add 100s of distinct tissue and developmental-stage-specific non-protein regulatory molecules, each controlling expression of 100s of genes: expand coding potential complexity. ;RNA Interference and MicroRNAs: Tip of the Iceberg? “Most stunning development of the last decade”: discovery of multiple unexpected phenomena under RNA interference (RNAi). And, parallel development of the microRNA (miRNA) field. Disregardi