[基础科学]动物体内植入镁合金的早期实验研究.pdfVIP

w w Vol No w o ACTA METALLURGICA SINICA Nov pp RNIF aZY


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MKtdWctBg MKWcvBg O J Jy AZB iXAPe zlXhcaQiXPess PesLaMviXA TAToGH TGHHsciXA msbqnAGsAWmiWfLDfDZrNsiD CCPeaviXAWslmFGHsh dkGSiXS S TG Bt A Ps EXPERIMENTAL STUDY OF IN VIV O IMPLANTATION OF A MAGNESIUM ALLOY AT EARLY STAGE




ZHANG Guangdao HUANG Jingjing YANG Ke ZHANG Bingchun AI Hongjun Scho ol of Stomatology China Medical University Shenyang Institute of Metal Research Chinese Academy of Sciences Shenyang Correspondent AI Hongjun pr ofessor Tel Email aih yahoocomcn Manuscript received in revised form ABSTRACT In order to study b oth the eect and the degradation b ehavior of magnesium alloys ted in the NewZealand onin animals AZB magnesium alloys with dierent dimensions were implan rabbits and compared with a titanium alloy TiAlV as a control material It was found from the exp eriments that the osteotylus was formed surround the magnesium alloy implant after weeks which was turned into rip e b one tissue after weeks The implantation of the magnesium alloy did not show negative inuence on the recirculating immune and urinary systems of the rabbits Magnesium calcium apatite which was the main degradation pro duct of the magnesium alloy could b e metab olismed by the kidney Magnesium ion concentration in the blo o d was in the range of normal values It can b e concluded that the magnesium alloy implantation is safe for rabbits at the ear