结节病影像学特点英文 ppt课件.ppt

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结节病影像学特点英文 ppt课件

Pulmonary Sarcoidosis: Typical Manifestations at High- Resolution CT with Pathologic Correlation Recent Advances in Sarcoidosis 结节病CT典型表现结节病进展 Sarcoidosis is a multisystem disorder that is characterized by noncaseous epithelioid cell granulomas, which may affect almost any organ. 结节病是一种以非干酪样坏死的上皮细胞肉芽肿为特点的多系统疾病, 几乎可以累及所有器官。 Sarcoidosis may be asymptomatic or chronic. It commonly improves or clears up spontaneously(自愈或好转). More than 2/3 of people with lung sarcoidosis have no symptoms after 9 years. About 50% have relapses. About 10% develop serious disability. Sarcoidosis of the lung is primarily an interstitial lung disease in which the inflammatory process involves the alveoli, small bronchi, and small blood vessels. Typical and Atypical Features of Pulmonary Sarcoidosis at High-Resolution CT Typical features 1 Lymphadenopathy: hilar, mediastinal (right paratracheal), bilateral, symmetric, and well defined 2 Nodules: micronodules (2–4 mm in diameter; well defined, bilateral); macronodules (≥5 mm in diameter, coalescing) 3 Lymphangitic spread: peribronchovascular, subpleural, interlobular septal 4 Fibrotic changes: reticular opacities, architectural distortion, traction bronchiectasis, bronchiolectasis, volume loss Bilateral perihilar opacities 5 Predominant upper- and middle-zone locations of parenchymal abnormalities 结节病原本是肺间质性病变,累及肺泡,支气管和小血管 淋巴结增大,两侧对称,境界清楚 大小结节 淋巴管播散,支气管血管鞘,胸膜下,小叶间隔 纤维化改变,网状阴影,肺结构扭曲,牵拉性支扩,肺容积缩小,两肺门旁致密影 中上肺为主 典型特征 Pathologic Correlation 相关病理 Granulomas in the lung parenchyma have a characteristic distribution in relation to lymphatics in the peribronchovascular interstitial space, subpleural interstitial space, and, to a lesser extent, the interlobular septa (ie, a lymphangitic distribution) 肺实质肉芽肿分布与支气管血管鞘,胸膜下结缔组织,小叶间隔中淋巴管相关 Thickened bronchovascular bundles and small perivascular nodules seen at CT corresponded to granulomas within the connective tissue sheath surroun

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