[精品]PCI患者围术期的抗血小板治疗.pptVIP

* 血小板不仅参与了动脉粥样硬化的发生与发展，更重要的是，血小板活化与动脉粥样硬化血栓形成密切相关。如图所示。 国际权威指南都明确推荐抗血小板治疗是ACS二级预防的基本措施。 * 这是稳定斑块和部稳定斑块的示意图。不稳定斑块的纤维帽非常薄，在血液剪切力的作用下纤维帽的肩部特别容易破损，造成斑块破裂形成血栓，导致患者再发缺血性血管事件。 Atherosclerotic plaque has 2 main components: a soft, lipid-rich core and a hard, collagen-rich fibrous cap. In stable plaques, a thick fibrous cap may represent 70% of plaque volume. It stabilizes the plaque and prevents it from undergoing rupture. In contrast, unstable plaque has a thin fibrous cap and is at greater risk for rupture. In unstable plaque, the lipid-rich core may represent the majority of the plaque volume. The