[理学]第6章主要组织相容性复合物.pptVIP

第六章 主要组织相容性复合物 (Major Histocompatibility Complex, MHC) Table of Contents S1: Discovery of MHC S2: Definition of MHC S3: Genes of MHC S4: The Structure of MHC molecules S5: Function of MHC S6: HLA与人类疾病 Section 1 Discovery of MHC Discovery of MHC in mouse Inbred strain(近交系小鼠) (1920) Experiments by Gorer (1936) Experiments by Snell (1948) Congenic strain(同类系小鼠) inbred strain Experiments by Gorer 在鉴定inbred strain小鼠血型抗原时曾发现4组红细胞抗原，I，II，III，IV。 其中抗原II只存在于某些品系而不存在于另一些品系小鼠中。 Experiments by Snell Method: Study the possibility of transferring tumor cells from one strain to another. Re