得到的化合物称为神经酰胺.ppt

Sphinx 狮身人面像 * 磷脂如甘油磷脂或鞘氨醇磷脂 * 注意，此非投影式 * 头部X基团电性的差异可以极大的改变膜表面的性质 －5？ * 心脏中一半的磷脂是缩醛磷脂 纤毛虫，嗜盐细菌中含醚脂较多 为什么需要醚键连接的甘油磷脂？不知道 推测可能与其对抗磷脂酶有关 * 由嗜碱性粒细胞释放，刺激血小板聚集并释放5－羟色胺，一种刺激血管收缩的因子。在过敏反应和发炎过程中起作用 当体内5-羟色胺水平升高时，血管收缩；当5-羟色胺水平降低时，血管扩张，而血管的扩张可能会引起偏头痛或其他疾病。 It causes platelets to aggregate and blood vessels to dilate. Thus, it is important to the process of hemostasis（止血）. At a concentration of 10?12 mol/L, PAF causes life threatening inflammation of the airways to induce asthma like symptoms. ... 活性物质如组胺、缓激肤、5－羟色胺和血小板激活因子等，导致全身毛细血管扩张和通透性增加，心排血量急剧减少，血压下降达休克水平 5羟色胺 it is actively taken up by blood platelets, which store it. When the platelets bind to a clot, they disgorge serotonin, where it serves as a vasoconstrictor and helps to regulate hemostasis and blood clotting. paf本身的作用是使血管舒张，而五羟色胺本身作用是使收缩 Hemostasis occurs when blood is present outside of the body or blood vessels. It is the instinctive response for the body to stop bleeding and loss of blood. During Hemostasis three steps occur in a rapid sequence. Vascular spasm is the first response as the blood vessels constrict to allow less blood to be lost. In the second step, platelet plug formation, platelets stick together to form a temporary seal to cover the break in the vessel wall. The third and last step is called coagulation or blood clotting. Coagulation reinforces the platelet plug with fibrin threads that act as a “molecular glue”.[1] Platelets are a large factor in the hemostatic process. They allow for the creation the “platelet plug” that forms almost directly after a blood vessel has been ruptured. Within seconds of a blood vessel’s epithelial wall being disrupted platelets begin to adhere to the sub-endothelium surface. It takes approximately sixty seconds until the first fibrin strands begin to intersperse among the wound. After several minutes the platelet plug is completely formed by fibrin.[2] Hemostasis is maintained in the body via three mechanisms: Vascular Spasm - Damaged blood vessels co