多因素介入对糖尿病的影响.pptVIP

Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes ;Diabetes Background;Diabetes Complications;Steno-2 Study: Intensive therapy vs. conventional therapy for DMII (2003);Steno-2 Follow-up: Effect of a Multifactorial Intervention on Mortality in Type 2 Diabetes (2008);Original Steno-II Selection Criteria;Steno-II Intensive Therapy;Steno-II Intensive Therapy (cont);Steno-II f/u Endpoints;Statistical Analysis;Results;Clinical Characteristics (cont);1o Endpoint: Cumulative Incidence of Death;2o Endpoints: Death from a CV cause;2o Endpoints: Number of CVD events;3o Endpoints: Microvascular Complications;1o Endpoint – 30% death rate in intensive therapy group vs. 50% in the conventional group over 13.3 years (ARR = 20%, P = 0.02).;1. Length of the study;Weaknesses/Limitations;Impact on Clinical Practice;Future Directions in Diabetes;References