肾素-血管紧张素系统活化.docVIP

心力衰竭的神经体液代偿机制 高莉 王峻瑶 刘赛 周越 艾富强 （北京大学基础医学院 05级临床4班） 摘 要 心力衰竭代偿机制包括全身交感神经和肾素-血管紧张素系统的激活。通过增加钠、水重吸收，外周血管收缩，心肌收缩力增强等维持机体稳态，但过度代偿却对机体有害。本文将详细阐入其具体机制。 关键字 心衰，交感神经系统，肾素-血管紧张素 Abstract The compensatory mechanisms of heart failure that have been described include activation of the adrenergic nervous systemic and renin angiotensin system (RAS), which are responsible for maintaining cardiovascular homeostasis through increased retention of salt and water, peripheral arterial vasconstriction and increased contractility, etc. But the excess compensation may exert harmful effects. The detailed mechanisms w