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Physiology of Reproduction(I) Teng Yincheng M.D., Ph.D., Professor Department Of Obstetrics Gynecology Renji Hospital Affiliated to SJTU School of Medicine Two Major Phases of Female Reproductive Function Preparation of the body for conception Pregnancy 1.Women’s Physiological Stages Neonatal period: birth---4 weeks Childhood: 4 weeks----12 years Puberty: 12 years---18 years Sexual maturation: 18 year---50 year Perimenopause: decline of ovarian function (40 years)----1 year postmenopause Postmenopause: 2.Menstruation Menstruation cyclic endometrium sheds and bleeds due to cyclic ovulation and ovarian hormones changes Mense Endometrium is sloughed (progesterone withdrawal) Nonclotting menstrual blood mainly comes from artery (75%) Interval: 24-35 days (28 days). duration: 2-6 days. the first day of menstrual bleeding is consideredy by day 1 Shedding: 30-50 ml 4.The Ovarian Cycle and Hormones 2)Ovarian Follicular Growth(Each ovum is enclosed within a follicle) The Ovary and Process of Ovulation 2)Estrogen effects on the Uterus External Female Sex Organs Tissue enlargement: fallopian tubes, uterus, vagina, and all external genitalia Vaginal epithelium: Cuboidal into stratified type; increase resistance to trauma and infection Facilitate transport of fertilized ovum toward uterus: Increase fallopian cilia number tubelocking Proliferate endometrial glands in fallopian tubes and uterus: Nourish implanting ovum Other hormones Thyronine and triodothyronine Congenital adrenal hyperplasia ACTH 21-羟化酶缺陷—皮质激素合成不足---ACTH Progesterone and 17-羟孕酮-------testosterone 女性假两性畸形 Insulin –dependent diabetes millitus THANKS FOR YOUR ATTENTION Estrogen effects on: Breast development of ductile system, stroma tissues fat deposition ? matur
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