Diabetes and 30-Day Mortality From Peptic Ulcer Bleeding and….Image.Marked.pdf

E p i d e m i o l o g y / H e a l t h S e r v i c e s / P s y c h o s o c i a l R e s e a r c h O R I G I N A L A R T I C L E Diabetes and 30-Day Mortality From Peptic Ulcer Bleeding and Perforation A Danish population-based cohort study REIMAR W. THOMSEN , MD, PHD1,2 METTE NØRGAARD, MD1 ulcer healing (10), blurring of symptoms ANDERS RIIS, MSC1 HENRIK T. SØRENSEN, MD, DMSC1,3 due to autonomic neuropathy, and in- STEFFEN CHRISTENSEN , MD1 creased risk of bacterial sepsis (11). Very limited data on the association between diabetes and outcome after peptic ulcer OBJECTIVE — Diabetes may influence the outcome of complicated peptic ulcer disease, due complications are available, due to the to angiopathy, blurring of symptoms, and increased risk of sepsis. We examined whether dia- very large sample size needed to study betes increased 30-day mortality among Danish patients hospitalized with bleeding or perforated this issue. peptic ulcers. Research resources available in Den- mark allowed us to undertake a cohort RESEARCH DESIGN AND METHODS — This population-based cohort study took study within a population of 1.4 million place in the three Danish counties of North Jutland, Viborg, and Aarhus between 19