脊柱结核的微生物学诊断 课件.pptVIP

Microbiological diagnosis of spinal tuberculosis International Orthopaedics (SICOT) (2012) 脊柱结核的微生物学诊断;Abstract Purpose The purpose of this study was to review the clinical features and diagnosis of spinal tuberculosis cases reported in the literature. Methods A medical literature search in the Medline Pubmed database was undertaken to review tuberculosis spinal infection and extra-pulmonary tuberculosis diagnosis improvement. 摘要 目的：本研究的目的是回顾文献已报道的脊柱结核病例的临床特点及诊断。 方法：在MEDLINE PubMed数据库中进行了医学文献检索以便研究脊柱结核感染及肺外结核病诊断的改进。;We introduced the following search items and boolean operators: spinal infection, spinal tuberculosis infection, microbiological diagnosis of spinal tuberculosis and spinal tuberculosis PCR. Single cases or series without microbiological diagnosis were rejected. Manuscript language was restricted to Spanish, French, and English versions. 我们引用了以下的搜索项目和布尔运算符：“脊柱感染”，“脊柱结核感染”，“脊柱结核的微生物学诊断”和“脊柱结核聚合酶链反应。”未经微生物学诊断的单病例或系列研究被拒绝纳入。手稿语言仅限于西班牙语，法语和英语版本。;Results and conclusions Spinal tuberculosis is more common in developing countries and is probably underdiagnosed. Delayed diagnosis is characteristic; it worsens the prognosis and increases morbidity. The microbiological diagnosis is crucial for several reasons. Despite surgical treatment, medical treatment with anti-tuberculous drugs is always necessary. A total of 20–40% of the spinal tuberculosis patients show another locus of infection. 结果与结论 脊柱结核在发展中国家更为普遍且常被漏诊。延误诊断具有特征性，它使预后恶化并增加发病率。脊柱结核微生物学诊断的至关重要性有几种原因。尽管行手术治疗，抗结核药物治疗总是必要的，共有20-40%的脊柱结核患者表现出另有感染源。;Pulmonary location can become a public health problem. Previously treated patients for other tuberculosis locations, incomplete treatments, or poor adherence can change the M. tuberculosis sensitivity pattern. Drug resistance test becomes a major need in the microbiology laboratory. PCR diagnostic techniques advance the diagnosis and increase the sensitivity and specificity rate. 肺部结核病灶可以成为一个公共健康问题。先前治疗的其他部位结核病灶，不完全治疗或依从性差的患者可以改变结核分枝杆菌的敏感性。耐药性试验成为微生物学实验室中的主要需求。聚合酶