复旦大学上海医学院肿瘤学系1.pptVIP

Map with localization of geographic areas where BRCA1/2 mutation carriers were living Breast Cancer Res Tr. 110: 99-109; 2008 Case Report A 43 years old woman. PE: a 2cm mass in the upper-lateral quadrant of left breast. No mass in the right breast. B-US: a mass in the left breast, and no mass in the right one. Pedigree Mammography R L MRI Familial Adenomatous Polyposis Hundreds to thousands of adenomatous polyps at a young age Cancer occurs at an average age of 39 years Diagnosis -- Flexible sigmoidoscopy Prophylactic colectomy At risk for primary adenomas and carcinomas of the duodenum a