从6_APA和7_ADCA生产废液中回收苯乙酸.pdfVIP

# 260# ENV IRO NM EN TAL PRO TECT IO N O F CHEM ICA L IND U STRY 2007 27 3 6- APA 7- ADCA , , , , , ( , 050026 [] 6- 7 - - 3- ( ( PAA , : , 30 e 15 m in500 m L 130 mL , 96. 5% ; 65 e 10 e , PA A 89% , 99% ; PAA , G [] ; 6- ; 7 - - 3- ; [ ] TQ 116. 2 [] A [] 1006- 1878( 2007 0 3- 0260 - 03 Recovery of PhenylAcetic Acid from W aste Liquor in 6-APA and 7-ADCA Production L i L ijuan, Yu W enguo, J iang Cu ilan, Zhang Zh idong, M a L ifeng, Chen Hui ( D epartm en t of Ph arm aceut ical Eng ineering; H ebei Chem ical and Pharm aceut ica lV ocational T echno logy C o llege, Sh ijiazhuang H eb ei 050026, C h ina A bstract: Pheny l acetic acid ( PAA w as recovered from w aste liquor in 6-am ino-pen icillanic acid and 7-am ino-3-desace toxy cephalo spo ran ic acid product ion by ex traction w ith so lvent and w a ter. T he ef fects o f d ifferent facto rs on the recov ery w ere studied. U sing to luene as ex traction agent and under the optmi um conditions o f ex traction tem perature 30 e , ex traction tmi e 15 m in, ex traction ag ent do sage 130 m L in 500 m L w aste liquor, the ex tract ion eff ic iency is 96. 5% . W hen the w ater ex traction tem perature is 65 e and the cry sta lliz ation tem perature is low er than 10 e , the y ield o f PAA is abov e 89% and the purity is abo ve 99% . T he PAA product w ith good qua lity can be u sed in the production o f m edic ine such as penic illin G. K ey w ords: heny l acetic ac id; 6-am ino-penic illan ic ac id; 7-a