强吸附型纳米银溶液的研制及在医用抗菌辅料中的应用.docVIP

强吸附型纳米银溶液的研制及在抗菌医用敷料中的应用 张峰1，武娜娜1，徐思峻2，3，许丹晨2，陈宇岳3 （1．沙洲职业工学院纺织工程系，江苏，张家港 215600； 3．张家港耐尔纳米科技有限公司，江苏，张家港 215600；3．苏州大学纺织与服装工程学院，江苏，苏州 215021.） 摘要：以烷基化环糊精水溶液和硝酸银为原料，一步法制备了一种新型强吸附型纳米银溶液；采用透射电镜（TEM）表征纳米银溶液的形成，纳米银的粒径在5-10nm左右；以金黄色葡萄球菌（S.aureus）和大肠杆菌（E.coli）为例，测试纳米银溶液的抗菌能力，结果表明5ug/ml的纳米银含量即具有优异的抗菌性能，抗菌率达到99%以上；将纳米银溶液应用于烧烫伤抗菌网状纱布、烧烫伤抗菌水刺无纺布及海藻酸钙纤维止血垫等抗菌医用敷料，SGS的检测结果表明，均获得了满意的抗菌效果，体现了优异的应用前景。 关键词：纳米银；强吸附性能；抗菌医用敷料 Preparation of a nano-sliver solution with strong adsorption and its application to antimicrobial medical dressing ZHANG Feng1, WU Nana1，XU Sijun2，3, XU Danchen2, CHEN Yuyue3 (1. Department of Textile Engineering, Shazhou Institute of Technology, Zhangjiagang Jiangsu 215600; 2. Zhangjiagang Nellnano Technology Co.，LTD ，Zhangjiagang, Jiangsu 215600; 3.College of Textile and Clothing Engineering, Suzhou University, Suzhou , Jiangsu, 215021.) Abstract: Using alkylated cyclodextrin aqueous solution and silver nitrate as raw materials, a new type of nano-silver solution with strong adsorption was prepared by one-step method; the formation of nano-silver solution was characterized by transmission electron microscopy (TEM) , and the result showed that the particle size of nano-silver was about 5-10nm; antibacterial testing of nano-silver solution on Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) indicated that 5ug/ml nano-silver had excellent antibacterial properties, of which anti-bacterial rate was more than 99%. And then nano-silver solution was applied to antibacterial burns mesh gauze, antibacterial burns spunlace non-woven, calcium alginate fiber hemostatic pads and other antibacterial medical dressings, and SGS test results proved satisfied antibacterial effect, which indicated excellent application prospects. Keywords: Nano-silver; Strong adsorption performance; Antimicrobial medical dressing 在临床上，伤口很容易感染而不易愈合，这是由于伤口表面一般有一个温暖而且潮湿的环境，金黄色葡萄球菌、念珠菌和大肠杆菌等病原体在伤口上很快繁殖引起的。为了控制伤口细菌的繁殖，防止伤口感染，大量医用敷料被广泛应用于伤口覆盖保护，并在医用敷料使用的同时考虑加入抗生素或各种各样的抗菌材料，以协助控制止血、保护伤口、减