β的中海贫血的影像学表现.pdf

Radiological Manifestations of Radiological Manifestations of β-Thalassemia β-Thalassemia Vijay G. Sankaran, HMS III Gillian Lieberman, MD Our Patient Our Patient A 7 year old boy presenting in 1980 to the King Faisal A 7 year old boy presenting in 1980 to the King Faisal Specialist Hospital in Riyadh, Saudi Arabia. Specialist Hospital in Riyadh, Saudi Arabia. The child presented to the hospital with severe anemia, The child presented to the hospital with severe anemia, hepatosplenomegaly, and alterations in facial hepatosplenomegaly, and alterations in facial morphology. morphology. This patient was found to have β-thalassemia major. This patient was found to have β-thalassemia major. The child was initially seen in April of 1980 and a The child was initially seen in April of 1980 and a splenectomy was performed in June of 1980. splenectomy was performed in June of 1980. Our Patient: Chest X-Ray Taken on Our Patient: Chest X-Ray Taken on Presentation Before Splenectomy Presentation Before Splenectomy Findings: - Initial trabecular and cortical thinning - Later trabecular coarsening - Osteopenia Courtesy of Dr. F.M. Hall Our Patient: Chest and Abdominal Plain Our Patient: Chest and Abdominal Plain Films Following Splenectomy Films Following Splenectomy Impaired Ossification at the Ilium-Ischium-Pubic Interface Vertebrae Show BoneAbsence of the Spleen-in-Bone Appearance