地方病2017讲解课件.pptVIP

* * * * * * * * * * figure 5. Myxedematous endemic cretinism in the Democratic Republic of Congo. Four inhabitants aged 15-20 years : a normal male and three females with severe longstanding hypothyroidism with dwarfism, retarded sexual development, puffy features, dry skin and hair and severe mental retardation. From Delange (191). * 男性13岁， 膝关节（中图）干骺端不规则钙化增白，边缘毛糙。头颅侧位（下图）示囱门处颅缝宽，缝间骨特多，副鼻窦和乳突气化差。 呆小病因先天性甲状腺功能低下或丧失，使发育过程受阻，尤其表现在骨骼系统和神经系统，因而出现侏儒症。本病的主要表现是软骨生长和骨化延迟，骨化中心的出现和愈合均延迟。长骨的长度和宽度均不正常，10岁儿童的长骨长度仅相当于正常2-3岁儿童的长度。四肢长骨与躯干骨的比例亦不相称。 [影像学表现]???? 1.颅骨骨化延迟，可见囱门与颅缝久不闭合，颅底缩短，头颅宽度增大，蝶鞍变小，副鼻窦发育障