Metathesis Reaction 高等有机化学教材.ppt

Advanced Organic Chemistry(1)高等有机化学（I）;Last day to submit the group project member liststo:chem_homework1@126.com;Materials Website link/jkyang/courses.htm;/chemistry/laureates/2005/index.html;Schrock;Inductive Effect and Dipole Moment;Electron Effect and Conjugated Effect should be considered at the same time ;Electron donating : σ0Electron withdrawing : σ0;Chapter 1, Mechanism of Organic Reaction1.1 Mechanism and suggestion strategy1.2 Methods on the determination of mechanism1.3 Theory related to mechanism 1.3.1 Transition theory 1.3.2 Hammond Hypothesis 1.3.3 Curtin_Hammett Principle 1.3.4 Principle of Microreversibility  1.3.5 Kinetic Isotope Effects 1.3.6 Substituted Group Effects 1.3.7 Some examples;Main Topics in 9/29;1.3.6 Substituted Group Effects;1.3.6 Substituted Group Effects;π-πconjugative system characteristics: alternate (交替)single and double bonds; two or more double bonds may involved in the conjugative system： ;Unsaturated conjugated system may undergo different reaction to the same substituted group Because of conjugated effect !!!!!;.2 Conjugated Effects;.3 HyperConjugated Effects Hyperconjugation is the stabilising interaction that results from the interaction of the electrons in a σ-bond (usually C-H or C-C) with an adjacent empty (or partially filled) p-orbital or a π-orbital to give an extended molecular orbital that increases the stability of the system. Based on the valence bond model of bonding, hyperconjugation can be described as double bond - no bond resonance but it is not what we would normally call resonance, though the similarity is shown below. ;key difference between hyperconjugation and resonance Hyperconjugation involves a sigma orbital component, usually a C-C or C-H bond.Resonance involves pi orbitals;First we need to draw it to show the C-H σ-bonds. Note that the empty p orbital associated with the positive charge at the carbocation centre is in the sa