lighttnfsf14)作为hpv16 e7 dna疫苗佐剂在宫颈癌治疗中的作用研究-study on the role of lighttnfsf 14 ) as hpv 16e7 dna vaccine adjuvant in the treatment of cervical cancer.docxVIP

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lighttnfsf14)作为hpv16 e7 dna疫苗佐剂在宫颈癌治疗中的作用研究-study on the role of lighttnfsf 14 ) as hpv 16e7 dna vaccine adjuvant in the treatment of cervical cancer.docx

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lighttnfsf14)作为hpv16 e7 dna疫苗佐剂在宫颈癌治疗中的作用研究-study on the role of lighttnfsf 14 ) as hpv 16e7 dna vaccine adjuvant in the treatment of cervical cancer

5.实验结果···················································································································596.讨论·························································································································657.参考文献···················································································································66第四部分：LIGHT/E7DNA联合顺铂化疗对C57BL/6-TC-1宫颈癌模型的免疫治疗效应研究1.中文摘要···················································································································682.英文摘要···················································································································693.前言·························································································································714.材料和方法···············································································································725.实验结果···················································································································746.讨论·························································································································797.参考文献···················································································································80全文总结·······················································································································81文献综述·······················································································································82免疫佐剂的研究进展····································································································82致谢·····························································································································93LIGHT（TNFSF14）作为HPV16E7DNA疫苗佐剂在宫颈癌治疗中的作用研究博士研究生：李莉导师：马丁教授华中科技大学同济医学院附属同济医院妇产科/肿瘤生物学研究中心中文摘要虽然宫颈癌的预防和治疗方法有了很大的进步，但是就全世界范围而言，宫颈癌的发病率和死亡率仍然很高。传统的以手术结合放化疗的治疗方法辅以免疫治疗将有望成为宫颈癌治疗的主要手段。众所周知，宫颈癌的发生发展与人乳头瘤病毒（HPV）持续感染存在必然相关性，HPV早期蛋白E