慢性乙型肝炎三联疗法、中医免疫辨证三环治疗观察.docVIP

慢性乙型肝炎三联疗法、中医免疫辨证三环治疗观察 　　[摘要] 目的：观察三联疗法、中医免疫辨证三环治疗慢性乙型肝炎的临床疗效。方法：将我院2009年1～12月收治的96例慢性乙型肝炎患者随机分为观察组和对照组。观察组48例患者采用三联疗法、中医免疫辨证三环治疗，对照组48例患者采用传统药物治疗，对比两组的临床疗效。结果：对照组总有效率为77.08%，观察组总有效率为91.67%，观察组疗效显著优于对照组，两组比较差异有高度统计学意义（P 　　[关键词] 慢性乙型肝炎；三联疗法；中医免疫辨证三环治疗 　　[中图分类号] R512.62 [文献标识码] A [文章编号] 1673-7210（2011）07（a）-100-02 　　 　　The observation on triple therapy and triple ring of TCM immune discrimination in the treatment of chronic hepatitis B 　　ZENG Guolu 　　Department of Traditional Chinese Medicine, Xixiang Peoples Hospital of Baoan District in Shenzhen City, Guangdong Province, Shenzhen 518101, China 　　[Abstract] Objective: To observe the clinical efficacy on triple therapy and triple ring of TCM immune discrimination in the treatment of chronic hepatitis B. Methods: 96 patients with chronic hepatitis B in our hospital from January 2009 to December 2009 were divided randomly into two groups, 48 patients in the observation group were given triple therapy and triple ring of TCM immune discrimination, 48 patients in the control group were given traditional medicine therapy, and the clinical efficacy of the two groups were compared. Results: The total efficiency of the control group was 77.08%, the observation group was 91.67%, the observation group was significantly better than that of the control group (P0.05），具有可比性。本次选择的96例病例资料中排除肝恶性肿瘤患者，严重心、肾、肝、肺功能不全者，重大手术或严重创伤恢复期患者以及正处于激素治疗期患者。 　　1.2 方法 　　1.2.1 治疗方法 　　对照组给予甘利欣注射液30 ml，以10%葡萄糖注射液稀释后静脉滴注，每日1次，3个月为1个疗程，共2个疗程，同时给予维生素C、肝泰乐、极化液等常规药物治疗。观察组在对照组治疗基础上给予三联疗法、中医免疫辨证三环治疗，3个月为1个疗程，共2个疗程。 　　1.2.2 三联、三环疗法 　　1.2.2.1 三环针法 免疫介入轻度者采取苦参注射??（1号），于双侧足三里各注射3 ml；免疫介入中、重度者根据中医辨证原则取穴，阳虚者取双侧阳陵泉穴，每侧注射3 ml苦参注射，阴虚者取双侧足三里穴每侧注射3 ml黄芪注射液（0号），阳虚与阴虚者均于双侧曲池穴，每侧注射黄芪注射液3 ml。 　　1.2.2.2 三环炙法 选用纯中药制剂的外用发泡剂奇雄丹。免疫介入轻度者取双肝俞穴与肠俞穴作为一组，双期门穴、关元穴与气海穴为第二组，两组替换外敷用药，炙量为常规量的2/3，每周1次；免疫介入中度者，肝俞、太冲为一组，期门与三阴交为第二组，两组替换外敷用药，炙量为常规量的2/3，三阴交炙量为常规量的1/2，若总胆红素（TBIL）51 μmol/L，甲胎蛋白（AFP）100 ng/ml或谷丙转氨酶（ALT）2～4周以后仍未出现下降者则肝俞、太冲、期门与三阴交暂停治疗，改取肝俞穴1/2量，每2周治疗1次；免疫介入重度者，肝俞穴为2/3炙量，三