CRISPRCas9 System细胞生物学教学教材.pptxVIP

——A New Way for Genome Editing;;;CRISPRs were first found in the E. coli genome in 1987(Ishino et al., 1987) These sequences exist in about 40% of all sequenced bacterial genomes The spacers of CRISPR and the gene of invaders are homologous clustered regularly interspaced short palindromic repeats(CRISPR,集群定期中间短回文的重复序列);;Artificial editing system——CRISPR/Cas9;The repairing system;修复引起突变;Process;New CRISPR/Cas9 System;Application;Application——An intracellular defense against HIV-1 infection;Advantages;Problem;Reference;k