糖尿病英文课件.pptVIP

Beijing Xuanwu Hospital Diabetes Mellitus Diabetes Mellitus definition types symptoms diagnosis Laboratory findings treatment complications Definition-WHO (4/2000) The term diabetes mellitus describes a metabolic disorder of multiple aetiology characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both Definition A metabolic condition characterised by high plasma glucose levels and chronic vascular complications A vascular disease affecting small and large arteries with coexistent metabolic disturbance particularly high plasma glucose levels Diabetes Mellitus definition types symptoms diagnosis Laboratory findings treatment complications Aetiological Classification of Disorders of Glycaemia Type 1 (beta–cell destruction, usually leading to absolute insulin deficiency) : Autoimmune: Idiopathic Type 2 (may range from predominantly insulin resistance with relative insulin deficiency to a predominantly secretory defect with or without insulin resistance) Other specific types Genetic defects of beta–cell function Genetic defects in insulin action Diseases of the exocrine pancreas Endocrinopathies Drug– or chemical–induced Infections Uncommon forms of immune–mediated diabetes Other genetic syndromes sometimes associated with diabetes Gestational diabetes Type 1 diabetes Previously known as IDDM(Insulin dependent diabetes) Ketosis prone:Usually diagnosed in younger age group(30 years) (Peak incidence 11-13 yr) Prevalence highly variable but approximately 0.20% with an incidence of 15-20 per 100000 population aged less than 21 Seasonal variation- with lowest rate in spring and summer Type 1 diabetes mellitus Immune-mediated type 1 diabetes acute LADA latent autoimmune diabetes in adults Idiopathic type 1 diabetes mellitus Type 1 diabetes mellitus Genetics Environmental factor Viruses Chemical agents Autoimmune Aut