新生儿胆红素代谢_《儿科学》精品课件(华西8年制).pptVIP

Chen Dapeng MD, PhD Pediatric Department West China Second University Hospital To understand the characteristics of neonatal bilirubin metabolism. Objective Jaundice(黄疸) Term baby (37w) 50% Incidence in Newborn Preterm baby(37w) 80% Core of Bilirubin Metabolism Unconjugated bilirubin (未结合胆红素) Conjugated bilirubin （结合胆红素） glucuronic acid （葡萄糖醛酸） Metabolism of Bilirubin Metabolism of Bilirubin Red Blood Cell Increase of bilirubin production Adult 3.8mg/L Newborn 8.5mg/L RBC life span 120 d 80 d RBC Quantity 4.5x1012/L 6.5x1012/L 2.Lack of Albumin(白蛋白) 3.Poor hepatic function Unc