医学赫赛汀胃癌肿瘤.pptVIP

既往的化疗药物治疗晚期胃癌的中位总生存期均在1年以下，ToGA研究是第一个治疗组生存期超过一年的晚期胃癌国际多中心III期临床研究，赫赛汀联合化疗组的中位OS达到13.8个月，而在HER2高表达患者中，赫赛汀联合化疗组的中位OS更是达到了16.0个月。具有跨时代的意义。 Reference： 1. Murad AM, et al. Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer. Cancer. 1993 Jul 1;72(1):37-41. 2. Vanhoefer U, et al. Final results of a randomized phase III trial of sequential high-dose methotrexate, fluorouracil, and doxorubicin versus etoposide, leucovorin, and fluorouracil versus infusional fluorouracil and cisplatin in advanced gastric cancer: A trial of the European Organization for Resea