rhorock信号通路 cd8t细胞参与eae发病的机制及fasudil干预分析-mechanism of rho rock signal pathway cd8t cells participating in eae and fasudil intervention analysis.docxVIP

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rhorock信号通路 cd8t细胞参与eae发病的机制及fasudil干预分析-mechanism of rho rock signal pathway cd8t cells participating in eae and fasudil intervention analysis.docx

rhorock信号通路 cd8t细胞参与eae发病的机制及fasudil干预分析-mechanism of rho rock signal pathway cd8t cells participating in eae and fasudil intervention analysis

ConclusionsRhoA,Rock-Ⅱ,CD8+TcellsinthepathogenesisandprogressionofEAEplayanimportantrole.RhoA,Rock-IIandtheexpressionofCD8+TcellsinEAEmodelchangesanddevelopmenttrendofsingle-phaselinecourse.Fasudilbyinhibitingtheinflammatoryresponse,thedualroleofpromotingnerveregeneration,reduceEAEsymptomsandimproveprognosis.【Keywords】experimentalautoimmuneencephalomyelitis;multiplesclerosis;RhoA;Rock-II;CD8+Tcell;Rhokinaseinhibitor;缩略词表EAEExperimentalautoimmuneencephalomyelitis实验性自身免疫性脑脊髓炎MSMultiplesclerosis多发性硬化CFAFreudscompleteadjuvant福氏完全佐剂CNSCentralnervoussystem中枢神经系统GPSCHGuineapigspinalcordhomogenate豚鼠脊髓

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rhorock信号通路 cd8t细胞参与eae发病的机制及fasudil干预分析-mechanism of rho rock signal pathway cd8t cells participating in eae and fasudil intervention analysis.docxVIP