高表达Ang1基因地间充质干细胞株地建立及其肺内转化研究.pptVIP

高表达Ang1基因的间充质干细胞的建立及其肺内转化研究 徐金富 瞿介明 李惠萍等 同济大学附属上海市肺科医院 复旦大学附属华东医院 High promise for angiopoietin-1(Ang1) in lung injury intervention Ang1 decreased in LPS induced lung injury anti-inflammation: inhibits endothelial permeability, neutrophil adherence and IL-8 production Anti-apoptosis role to endothelial cells Mesenchymal stem cells (MSC) No ethical difficulties harvest MSC from the individual to be treated No rejection problems Self migrate to where the injury is located Methods and results pCR2.1-Ang1 : Prof. Federico Bussolino in Institute for cancer research and treatment, Italy Electropho