儿童过敏药物（Allergic drugs for children）.docVIP

儿童过敏药物（Allergic drugs for children） Antihistamines anti allergic drugs are divided into the first generation antihistamines, second generation antihistamines and third generation antihistamines, currently with diphenhydramine, chlorpheniramine and promethazine as the representative of the first generation antihistamines are replaced with CNS strong inhibitory and will gradually be built with no sedation or sedation the role of small second generation antihistamines. As part of the second generation antihistamines have obvious toxicity due to the invention of the heart and gradually cut the application (such as terfenadine, aspirin and imidazole etc.). Non terfenadine, levocetirizine and three generation antihistamines have been published. At present, more than 20 kinds of second generation antihistamines have been applied in the world, while the third generation is only a few species. The second generation and the third generation of antihistamines can be used in the prevention and treatment of allergic asthma. At present, there are only 10 kinds of anti allergic drugs in our country, mainly for the second generation of antihistamines. As a side effect of loratadine and cetirizine, the clinical curative effect of non terfenadine and 2002 listed levocetirizine and 1999 listed with both drugs is similar, but more safety, fewer side effects, which is loratadine and cetirizine application in years cut. While non terfenadine and levocetirizine has become the world anti allergic drugs market sales increased drug fastest, accounting for about 30% market share, so the two drugs will be applied after a few years the worlds more extensive anti allergic drugs. In addition in recent years listed loratadine products desloratadine (Dlarinex) has entered the clinic in more than 30 countries, and has entered the Chinese market, although the drug is still not received FDB approval, but to enter the Chinese market the first third generation of anti allergy drugs, so in the huge marke