生存时间资料分析方法.pptxVIP

第一节 生存时间资料的特点;一、基本概念;;二、资料特点;三、统计描述;1.死亡率、死亡概率、生存概率;;;2.生存率、生存曲线、半数生存期;;;;第二节 小样本生存率的Kaplan-Meier估计;SPSS演示;小样本生存率的Kaplan-Meier估计, 例12-2 View Variable:;Analyze ?Survival ? Kaplan-Meier… Time 框:t Status框: c Define Event… Single Value: 1 Continue Options … Survival tables Mean and median survival Survival Continue OK;第三节 大样本生存率的寿命表法估计;SPSS演示;大样本生存率的寿命表法估计, 例12-3 View Variable:;Data ?Weigh Cases … Weigh Cases by: Frequency Variable 框：f OK Analyze ?Survival ? Life Tables… Time 框:t Display Time Intervals:10 by 1 Status框: c Define Event… Single Value: 1 Continue;第四节 生存曲线比较的假设检验;Log rank检验的基本思想;SPSS演示;生存曲线比较的Log rank检验, 例12-4 View Variable:;Analyze ?Survival ? Kaplan-Meier … Time 框:t Status框: c Define Event… Single Value: 1 Continue Factor框: g Compare Factor … Log rank Continue ;第五节 Cox比例风险模型;;SPSS演示; View Variable:;View Data:;Analyze ?Survival ? Cox Regression… Time: time Status: status (1) Covariates:group gender age cost duration complica obstruct size stage hb stb alt ast alp rgt wbc Method: Enter/Forward LR Plots:Survival Options … CI for exp(B):95% Continue OK;; View Variable:;View Data:;Analyze ?Survival ? Cox Regression… Time:生存时间 Status:是否死亡(1) Covariates: Ag阴阳性 白细胞数 Method: Enter Categorical: Categorical Covariates: Ag阴阳性 Plots:Survival Hazard Options … CI for exp(B):95% Continue OK