组织学skinppt课件.pptVIP

5. Stratum corneum: eosinophilic horny cell, filled with Keratin no desmosome, continuous shed * * Skin and Skin Appendages constitution: epidermis dermis function: protection sensory regulation secretion absorption thick skin, thin skin skin（largest organ） I. Epidermis keratinized stratified squamous epithelium consist of 5 layers keratinocytes + nonkeratinocytes Photomicrograph of a section of thick skin. Note the blood vessels in the dermal papillae improving the nutrition of the thick epithelium. Picrosirius-hematoxylin stain. Medium magnification. Photomicrograph of a section of thin skin. The stratum corneum is thinner than that in thick skin. 1. Stratum basale LM: a single layer of basophilic columar/cuboidal cells, rest on BM EM: ribosome, keratin filaments, desmosome and hemidesmosome Stem cell (mitotic activity) 2. Stratum spinosum LM: 5-10 layers, polygonal spinous processes EM: bundled K.F. ( LM:Tonofilaments) lamellar granules desmosomes Stratum spinosum of the skin from the sole of the foot (thick skin) showing the spiny projections that strongly bind the cells of this layer together to resist abrasion. Pararosaniline-toluidine blue stain. Medium magnification. 3. Stratum granulosum LM: 3-5 layers, spindle, basophilic EM: Keratohyalin granules (basophilic, no membrane, containng protein); Abundant L.G. (excrete into inter- cellular space to strengthen the cell connection thicken the cell membrane). 4. Stratum lucidum: 3-4 layers of cell appear eosinophilic and transparent; no nucleus and organella; densely packed keratin filaments Cell. Cell. Cytoplasm Cell Morph. Junc. R. LG. Tf. KhG. K Memb. lle / Nu 1 Layer Des. ++ -- + -- --