功能性消化不良胃电图与胃排空检测的同步研究_论文.docxVIP

功能性消化不良胃电图与胃排空检测的同步研究 作者：唐红卫 刘莉 黄裕新 徐海峰 高巍 周润锁 尚磊 高峰 安晓丽 【关键词】 功能性消化不良 Comparison between electrogastrogram and gastric emptying in patients with functional dyspepsia 【Abstract】 AIM: To study the pathogenesis of functional dyspepsia (FD) by electrogastrogram and gastric emptying test. METHODS: According to the RomeⅡcriteria, patients with FD were classified into 3 subclasses. From each subclass, 10 patients were randomly chosen in this study. 10 Healthy volunteers were used as normal control. All the patients and volunteers underwent electrogastrogram examination and gastric emptying test. Gastric emptying test was performed using 99Tcmlabelled solid food. Patients with FD were divided into 2 groups according to the results of gastric emptying test: normal gastric emptying group and delayed gastric emptying group. Data were collected accordingly and statistic analysis was performed. RESULTS: ① 18 patients showed gastric emptying delay. In patients with FD, postmeal average amplitude (AP) and △AP reduced significantly (P）; ②In FD patients with normal gastric emptying, % showed abnormal electrogastrogram; ③ In the FD patients with delayed gastric emptying, % were abnormal in electrogastrogram and their postmeal AP and △AP decreased significantly（P）. CONCLUSION: Motility disturbance of stomach plays an important role in the pathogenesis of FD. Electrogastrogram and gastric emptying test have a good consistency in determining FD. 【Keywords】 functional dyspepsia; electrogastrogram; gastric emptying 【摘要】 目的: 通过胃电图与胃排空检测，研究功能性消化不良(functional dyspepsia, FD)的发病机制. 方法: 以FD患者为观察对象，依据罗马Ⅱ标准，将符合纳入标准的患者分为3个临床亚型，每型患者随机取10人为一组，并以10名健康志愿者作为对照组，分别做胃电图及胃排空检测. 胃排空检测后，再将30例FD患者分为2组，胃排空正常组和胃排空延迟组. 利用胃电图仪记录胃电变化，通过99Tcm标记的固体餐检测胃排空. 结果: ①30例FD患者中，胃排空延缓18例，占%，其中，溃疡样型4例，动力障碍样型7例，非特异性型7例. 与健康对照组比较，胃电图餐后平均振幅降低（P）；②胃排空正常组胃电图%异常,各项指标与健康对照组、胃排空延迟组比较均无显著性差异（P）;③FD胃排空延迟组胃电图%异常,就餐前后平均振幅差减小（P）. 结论: 胃运动障碍是FD发病的重要病理生理机制，胃电图与胃排空检测有较好的一致性. 【关键词】 功能性消化不良；胃电图；胃排空 0引言 功能性消化不良（functional dyspepsia