β-catenin mediates stress resilience through Dicer1microRNA regulation 20150115PPT.pptx

Reporter: Sheng-Lan Gao(高胜兰)Advisor: Xiao-Qing Tang(唐小卿)Continued exposure to chronic stress such as pressure from work, personal issue and the loss of the beloved, some people tend to express anxiety and depression, whereas others do not. PhenomenonDespite decades of research, the molecularpathophysiology of depression remains elusive. One molecular player implicated in neuropsychiatric illnesses, including depression, is β-catenin.molecularpathophysiology β-cateninDepressionβ-catenin is a glycoprotein and it is also a multi-functional protein.upregulation of gene expressioncell-cell adhesio