《MHC与移植》PPT课件.ppt

Major Histocompatibility Complex(MHC);Significance of the MHC;Progress in organ transplantation;Genetic barriers to transplantation;Principles of transplantation;GVH disease in humans;The human MHC genes;The mouse MHC genes;Polymorphism of MHC antigens (based on phenotype);Polymorphism of MHC genes(based on DNA sequence/ PCR);The inheritance of MHC genes;MHC products expressed on cells;Crossing overresults in new haplotypes;MHC products expressed on cells;Class-I expressed on all nucleated cells in man, and also on erythrocytes in mice.;Alloreactivity of T cells: MLR and CTL generation;Alloreactivity of T cells;;Tempo of rejection reaction;A, B DR matching and graft survival;Blood transfusion and graft survival;Immunosuppressive agents;Immunosuppressive agents;Removal of T cells from marrow graft;HLA and disease association