局部晚期非小细胞肺癌的同期放化疗进展协和王绿化课件.ppt

Received Mar 8, 2012, and in revised form Apr 19, 2012. Accepted for publication Apr 29, 2012 Conclusion Patients undergoing CCRT for NSCLC, pneumonitis risk is associated with the type of chemotherapy regimen, dosimetric parameters, and patient age. Fatal pneumonitis is uncommon but is associated with large doses per fraction, large V20, and lower-lobe tumors. Further research is needed to evaluate methods to mitigate pneumonitis risk in patients undergoing curative-intent CCRT. Poor Baseline Pulmonary Function May Not Increase the Risk of Radiation Induced Lung Toxicity Jingbo Wang, M.D.; Jianzhong Cao, M.D. ; Shuanghu Yuan, M.D.; Wei Ji, M.D.; Douglas Arenberg, M.D.; Jianrong Dai, Ph. D.; Paul Stanton, B.A. ; Daniel Tatro; Randall K Ten Haken, Ph. D.; Luhua Wang, M.D.; Feng-Ming (Spring) Kong, M.D., Ph.D. Accepted by International Journal of Radiation Oncology*Biology*Physics Correlation between PFTs and ≥ G2 SRILT Logistic regression for analytical variables Individual based scatter plot indicates no linear correlation between MLD and FEV1. Conclusion Age and MLD were independently correlated with SRILT. Lower baseline pulmonary function did not increase the risk of SRILT and might even be associated with lower probability of SRILT, Which suggests that poor PFTs should not be a contraindication to definitive radiation therapy. FEV1 may help predicting the risk for SRILT. * Three Clinical Research Topics in Radiotherapy of Locally Advanced NSCLC 2、New Radiation Techniques: 3DRT，IMRT, IGRT, 4D RT 3、Normal Tissue Protection： Radiation Pneumonitis and Esophagitis * 谢谢 THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS THANKS T