重庆地区人群中维生素D水平的研究-第三军医大学学报.DOC

某研究所体检人群中维生素D水平的研究杜伟1甘承文2郭海波2程佳2单幼兰1 1. 重庆医科大学附属第二院肝病实验室 2. 重庆金域医学检验所 重庆 400012 【摘要】目的：了解重庆地区人群维生素D营养状况。方法：用串联质谱分析仪检测送检人员血25一羟维生素D[25(OH)VitD]水平，据此确定营养状况。重庆金域医学检验所2012年1月8月体检人员3875例≤14岁组（657例）、15岁-44岁组（3019例）≥45岁组（199例）应用SPSSl30软件进行统计分析。结果：本研究中，年龄≤14岁组的25(OH)VitD水平严重缺乏、缺乏、不足、正常、过量所占的比例分别为1.52%、19.03%、9.44%、70.02%和0%；而在15-44岁组中,其水平缺乏、不足、正常、过量的比例分别为?60.09%、27.59%、12.32%和0%；在≥45岁组中各项比例又为84.92%、13.07%、2.01%和0%。统计结果表明：15岁-44岁组≥45岁组中，女性25(OHVitD平均水平较男性更为低下，差异有统计学意义（P＜0.01而≤14岁组无统计学意义；≥45岁组与15 -44岁组对比，25(OH)VitD水平随着年龄增加而降低，差异有统计学意义（P＜0.01）且≤14岁组中有严重缺乏的现象出现结论：61.62％的成人存在缺乏，26.69％的成人不足；且随着年龄的增加更加显著，超过45岁的成年人缺乏达到84.92%。女性25(OHVitD水平各组均无过量。70.02%的儿童正常，但是1.52%?的儿童严重缺乏，19.03%的儿童缺乏，应引起足够重视。 【关键词】缺乏 ，25(OH)VitD， 营养调查The Level of Serum 25 (OH) Vitamin D among the Normal Population in Chongqing. （DU Wei， GAN Cheng-Wen，CHENG Jia，GUO Hai-BoSAN You-Lan。Department of Clinical Laboratory， The Second Affiliated Hospital of Chongqing Medical University，Chongqing 400010，China） Abstract】 Objective To investigate the distribution of Vitamin D among the normal population in Chongqing. Methods Three thousand eight hundred and seventy-five health people with age between 3 to 71, who were collected from Kingmed Diagnostics (from January to August, 2012 ) for the study of the level of serum 25 (OH) Vitamin D, which were detected by API4000Lc-MS/MS. Software SPSS13.0 was used for statistical analysis. Result In this study, three age groups (1. age ≤14 years; 2. age between 15 to 44 years old; 3. age ≥45 years) were divided for analysis the level of serum 25 (OH) Vitamin D. In group1, the ratio of Vitamin D-sufficient and insufficient people was detected as 70.02% and 9.44%, but there still have 19.03 percent young people were considered Vitamin D-deficient, more-worse, 1.52% younger were found severely- deficient in VitD. Three levels of serum 25 (OH) Vitamin D (deficient, insufficient and sufficient) were used to compare the group2 and 3 as follow: 60.09% vs.84.92%, 27.59% vs. 13.07% and 13.3