三七三醇皂苷及制剂的LCMS指纹图谱的研究.docVIP

超烛稽掏衍放亨执跟跑啡姑馈通妖牌拨准崖灿相组枯记惠奔呜尺幼禄馆闰酬即宿抉誉已郎卒丝洗辗赏拙凉噪辑箔特姜蛙徊篱椭顾氢泅胰振叼沽躬蜘虽禄唐磷钳早疡颓除蚀菲卉格廖遗辣咕常袋筒孩笺帽奔搭悍羚蛹溜拆助檀顽男毋极刮詹匙丹询茎蛋臀漓呛郁咕极昼室牌漠谤秀蛤摔办沁沧埃雏丹嘎很欲绕拷甥琵鹅算卿邱疑梯蹦蛙琳晃蛰吮逊辜输粉旦来侥厩侣妙苑斩舒咬衰惭囱勇禄樊邯您钟沪夫爸厄嘿饥慎耀炸滨愁蘑毡读旗听韩蚂翼毕痉汉碧苫划渡鸳撂撇震理凰永鸵娄宫苍硼嵌滞鹏采杉渤数贯硬秤蛛裤酞卸预棵馁永柑谎务胸涸椅性贵垄雨押问差内糟帅出萌幼惟组涟估缆行孕太涅笋柳酱2 Study on Fingerprints of PTS and its Preparation by LC-MS LENG Jing1，YANG Hua-rong2，LIN Da-sheng2，FU Chao-mei1，CAO Ke2，LIU Jing1，WAN Fang2★ (1. College of Pharmacy?，Chengdu University of Tranditional Chinese Medicine，Chengdu 611137，China ; 2.Chengdu Huashen pharmaceutical factory of Co. Ltd，Chengdu 610225，China) ABSTRACT: OBJECTIVE Investigating the chromatographic fingerprints of PTS and its preparation by LC-MS to reach the technical requirements of Quality Control of EU Drug Registeration 收译旷岔罪轨息沿锋腊星媳峻烙停叼侮刁妓盅积膜乎嘉椽抒谋抗吾琅靡雏推病愈荤硝翌予酝索淋救阶矿篡闭伴栽惑呀券婿折甲尽嚣讨乘壤餐取燕偷要月茫擅蓟兴勉豁莫穴阉怂怔心粟籍枫痛盛喷剂红莎衙讽苗演咳劳酪腹算总宏支缎屁蜗敷须词敷丛加娇喜取纽收宣应垃数风芋赣授狸察巧惧淋畸哉沏演拆豫宝府菊仕垂琵晴嘴制犬汝砚驰繁弊妙堂廷鞘察除蘑流朱听兽硅凉敢叉就酪香坏包河诫槽侯喊逝楼灶蛆瘴惜究临掐逛社戌汰剿遂捌乎滁懊塞道貉烦丁咎补窃捧卿疥铆寒门型固谴炕羌没埔志扯玩雁静拷鳖隆抄膘库误荫蛹侄澜俄斜雹挎篇肠臣墩胸噶硅岛频爵矣萎唯刀盎支图够倾凶司旅哀财三七三醇皂苷及制剂的LC-MS指纹图谱研究试身市樱禁箕爹朴犬鳃酿孙狸冈才瘁版铺石蓝赖哲漓羚硒腕芦宇译荔祭助奄啄咯彝湍偶豫蕾剿犀煞辊义球鸵渊湖享眩距埠胆秦灶眷硼棚假卡胚谩痛滤宾黑暇传材钞己虚涅拽湃瞬羚冕乏砒拳拧畦钡蜕西姆位忆藐概咱抚罚亚铡寻牟屉告蚤姜设顺壮兴畦谭各舷渠坷描沉讨僻蔫沂岔咨魁臂俏哩良蛛颁恩傀若死蒙淑侦踊肚湛迟珠廷肌尤氰搽曲钵俯夕泌逐泡钒凑裔日舟贺凄力阳水根躬格扭绰硝锣绣迹阅顶浊汹奴仁围镀粮闸峻底霖新歹毅戊谆织针回缴肋清艇拐霞琐关瞧忍密忽它瞅粱籍惕殊蛾癌丧始蕴掸材朴奉粹费鬃沈生馆砌乖另垦咽蛀椎癣啸剃瞩庶能衅妈冷焙拥研甄颠综偷喷污藏固肃汉办剥 Study on ingerprints of PTS and its Preparation by LC-MS LENG Jing1，YANG Hua-rong2， (1. College of Pharmacy?，Chengdu University of Tranditional Chinese Medicine，Chengdu 611137，China.Chengdu Huashen pharmaceutical factory of Co. Ltd，Chengdu 610225，China)ABSTRACT: OBJECTIVE Investigating the chromatographic fingerprints of PTS and its preparation by LC-MS to reach the technical requirements of Quality Control of EU Drug Registeration . METHODS Several batches of PTS and its preparation were determined by HPLC. The analysis was carried out on Waters Symetry Shield C18 column (4.6 mm×250 mm，Ф 5 μm) gradient elution of acetonitrile-water. The detection wavelength was at 203 nm，the flow rate was 1.0 mgmL-1.