Electron Paramagnetic Resonance Biodosimetry in - HPS Chapters电子顺磁共振生物剂量计在HPS章.pptVIP

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Electron Paramagnetic Resonance Biodosimetry in - HPS Chapters电子顺磁共振生物剂量计在HPS章.ppt

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Electron Paramagnetic Resonance Biodosimetry in - HPS Chapters电子顺磁共振生物剂量计在HPS章

Electron Paramagnetic Resonance Biodosimetry in Teeth and Fingernails A. Romanyukha1,2, R.A. Reyes2, F. Trompier3, L.A. Benevides1, H.M. Swartz4 Outline EPR dosimetry basics In vitro X and Q dosimetry in tooth enamel In vivo tooth L-band dosimetry EPR dosimetry in fingernails Conclusions What is Electron Paramagnetic Resonance (EPR) ? Non-destructive magnetic resonance technique used to detect and quantify unpaired electrons. Absorption of ionizing radiation generates unpaired electrons (i.e., paramagnetic centers). The concentration of radiation-induced paramagnetic centers is proportional to the absorbed dose. EPR: Fundamentals and Principles There is a net absorption of energy from the microwave field at resonance because of a greater population of electrons are in the lower energy state. The process is non-destructive because the population difference reestablishes itself after the microwave field is turned off. Thus, the history of radiation exposure is not destroyed by EPR measurements. Typical frequencies and wavelengths required for resonance of a free electron in EPR measurements EPR dosimeters for partial body exposure Characteristics of EPR dosimetry Non-invasive Based on a physical process Not affected by biological processes such as stress Not affected by simultaneous damage that is likely to occur with irradiation such as wounds burns Applicable to individuals Measurements can be made at any interval after irradiation up to at least 2 weeks (fingernails) or indefinately (teeth) Can provide output immediately after the measurement Unaffected by dose rate Can operate in a variety of environments Systems can be developed so that they can be operated by minimally trained individuals In vitro measurements in tooth enamel samples (X and Q-bands) Extracted teeth can be available for in vitro EPR measurements EPR dosimetry with teeth is the only method which can reconstruct external gamma radiation doses (100 mGy) individually. Steps of the method T