Dr Amit Basak - Department of Chemistry：Amit巴萨克-化学系博士.pptVIP

* * Lecture 2 Importance of chirality:Many drug molecules are chiral. However they are sold as racemates. In most cases only one enantiomer is the active agent. The other enantiomer is usually inactive while in some cases they may be toxic. Example: anti inflammatory agent R isomer inactive S isomer is active S isomer is active R isomer inactive (non antiinflammatory) as well as nephrotoxic  Methyldopa (antihypertensive)  (S – isomer is active) These drugs are what are called synthetic drugs If the drug is a natural product , it is available in chiral form. Chiral Drug