Lymphatic Filariasis Epidemiology - 亚历山大图书馆.pptVIP

Lymphatic Filariasis B.Ganesh Regional Filaria Training Research Centre National Institute of Communicable Diseases Kozhikode. Lymphatic Filariasis Infection with 3 closely related Nematodes Wuchereria bancrofti Brugia malayi Brugia timori * Transmitted by the bite of infected mosquito responsible for considerable sufferings/deformity and disability * All the parasites have similar life cycle in man * Adults seen in Lymphatic vessels * Offsprings seen in peripheral blood during night Disease Manifestation Disease manifestation range from None Acute-Filarial fever Chronic-Lymphangitis, Lymphadenitis, Elephantiasis of genitals/legs/arms Tropical Pulmonary Eosinophilia (TPE) Filarial arthritis Epididimoorchitis Chyluria, etc. Distribution Prevalent world wide in the Tropics and Sub-tropical regions of Africa Asia Western Pacific Parts of Central South America Global Scenario Population at risk : 1.2 Billion No. of countries : 80 Mf carriers : 76 Million Diseased : 44 Million Hydrocele : 27 Million Lymphoedema : 16 Million TPE : 1 Million National Scenario Total Population : 110 C Population at risk : 45.4 C (in 16 States 5 UT’s) Total infected : 51.7 M (Wb - 99.4 % and Bm - 0.6 %) No. of diseased : 22.5 M Mf carriers : 29.2 M Hydrocele : 12.9 M Agent Factors Host Factors Man – Natural Host Age – All age (6 months) Max: 20-30 years Sex – Higher in men Migration – leading to extension of infection to non-endemic areas Immunity – may develop after long year of exposure (Basis of immunity-not known) Social Environmental Factors Associated with Urbanization, Poverty, Industrialization, Illiteracy and Poor sanitation. Climate: is an important factor which influences: The breeding of mosquito Longevity (Optimum temperature 20-300C Humidity 70%) The development of parasite in the vector Sanitation, Town planning, Sewage Drainage. Mode of Transmission Incubation Period Lymphatic Filariasis is transmitted by the bite of Infected mosquito which har