分子生物学 07 transcription_and_regulation_in_eukaryotes.pptVIP

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分子生物学 07 transcription_and_regulation_in_eukaryotes.ppt

分子生物学 07 transcription_and_regulation_in_eukaryotes

Chapter 07:RNA transcription and regulation in Eukaryotes RNA polymerase subunits Eukaryotic pols have 12 or more different subunits; All contain subunits homologous to the subunits of the E.coli RNA pol core (?2??’); at least five other subunits are common to three different RNA pols; Each RNA pol contains additional four or seven specific subunits. Similarities to bacterial polymerases Don’t require a primer; Synthesize RNA in 5’ to 3’ direction; RNA complementary to the antisense template strand. Difference to bacterial polymerases There are 3 RNA pols; Require more accessory factors for

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