p53可抑制戊糖磷酸途径pentosephosphate-河南师范大学.PPTVIP

* We next investigated whether p53 interacts with G6PD. * Flag-tagged p53 specifically associated with enhanced green fluorescent protein (eGFP) G6PD in vivo. Similarly, endogenous p53 interacted with endogenous G6PD. This interaction was enhanced when cells were treated with the proteasome inhibitor MG132 doxorubicin, both of which stabilized p53. * G6PD is a cytoplasmic protein, whereas p53 is present in both the cytoplasm and the nucleus, and consistently, the p53 - G6PD interaction occurred in the cytoplasm. 谢 谢 聆 听 * * 梁俊平 河南师范大学水产学院 水产动物营养与饲料研究室 p53 regulates biosynthesis through direc