临床医学专业-2016年美国感染病学会HAPVAP指南解读.pptxVIP

HAP/VAP指南解读 张 舸 概 念 HAP：hospital acquired pneumonia医院获得性肺炎 亦称nosocomical pneumonia，NP医院内肺炎，是指患者入院时不存在、也不处在感染潜伏期，而于入院48小时后发生的，由细菌、真菌、支原体、病毒或原虫等病原体引起的各种类型的肺实质炎症。 HAP was defined in the 2005 document as the presence of “new lung infiltrate plus clinical evidence that the infiltrate is of an infectious origin, which include the new onset of fever, purulent sputum, leukocytosis, and decline in oxygenation.” 概 念 VAP：ventilator-associated pneumoniae, 呼吸机相关性肺炎。 指经气管插管或切开进行机械通气48～72小时后发生的肺炎。 病死率 While all-cause mortality associated with VAP has been reported to range from 20% to 50%, the