人畜共患病毒性疾病精品ppt课件.ppt

Flavivirus;人畜共患病毒性疾病Viral Zoonosis;虫媒病毒（Arthropod-borne viruses，arboviruses）是通过节肢动物（ arthropod vectors）传播的病毒 The WHO definition is as follows Viruses ?maintained ?in nature principally, or to an important extent, through biological transmission between susceptible vertebrate ?hosts by haematophagus arthropods or through ?transovarian and possibly venereal transmission in arthropods ;虫媒病毒种类;在我国流行并经病毒分离证实的虫媒病有6种 流行性乙型脑炎 森林脑炎 登革热 基孔贡亚热 肾综合征出血热 新疆出血热;;Scientist collecting specimens from trapped rodents;Common characteristics ;Major Clinical Categories of Arboviral Disease;Genome;黄病毒 Flaviviruses;黄病毒生物学特性;节肢动物媒介Arthropod Vectors;Arthropod Vectors;动物宿主（Reservoirs）;传播环节;Man-Arthropod-Man Cycle ;Animal-Arthropod-Man Cycle;登革病毒 Dengue Virus;Mature Dengue-2 virus particles replicating in five day old tissue culture cells;;传播环节;临床特点;A large subcutaneous haemorrhage on the upper arm of a patient with dengue haemorrhagic fever. ;Lab Diagnosis;预防;流行性乙型脑炎病毒Epidemic Type B Encephalitis;病毒性状;Biological properties;Epidemiology;;致病性;;Aedes mosquito feeding;人被带毒的蚊虫叮咬后，绝大多数表现为隐性感染或仅轻微症状。只有少数发生脑炎。 病毒侵入人体，经两次病毒血症后，播散到全身，10天左右潜伏期，出现发热、寒战及全身症状。0.1%的患者病毒越过血脑屏障进入脑组织，造成脑实质炎症和脑膜病变，临床表现为突然高热、头痛、呕吐、惊厥、昏迷等脑膜刺激症状和脑炎症状。死亡率高达10%—30% 部分患者恢复后留下精神障碍、运动障碍等后遗症 ;Pathogenicity and Immunity;Laboratory Diagnosis;血清学诊断; 病毒分离 Virus isolation;预防 Prevention;Tick-borne encephalitis virus;Morphology Typically Flavivirus Transmitted by tick Can be found in Russia, Middle Europe, and Germany, Epidemic infection also occurs in northeastern China. Tick is the host and transmitted vector. Cause encephalitis Incubation : 10-14 days Diagnosis = JBV Prevention Prevent tick-biting is the key procedure Inactivated virus vaccine is available;JT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ!1cnyJT5grBMX-9juFQ#1cnyIT5gqBMX-8juFQ#1cnyIT5gqBMX-8juFQ#1cnyIT5gqBMX-8juFQ#1cnyIT5gqBMX-8