新生儿脓毒症 课件.pptVIP

CRP Values in the Blood In healthy adults: 0.8mg/ L In infants: 10mg/L Starts with in 4-6 hours after stimulation and peaks around 36- 48 hours. Biologic half life is 19 hours with 50% reduction daily after the acute phase stimulus resolves. Measuring CRP concentration in CSF is unreliable. Cell Surface Markers and Granulocyte Colony Stimulating Factors Neutrophil CD 11b and CD 64 appear to be promising markers. CD 64 had sensitivity of 80% and specificity of 79% in culture proven sepsis. CD 11b had a sensitivity of 96- 100% and specificity of 81- 100% in culture proven sepsis. GSF, mediator