双酚a与氯化镉对mcf-7细胞增殖及wisp-2和bcl-2蛋白表达作用-effects of bisphenol a and cadmium chloride on proliferation and expression of wisp - 2 and bcl - 2 proteins in mcf - 7 cells.docxVIP
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双酚a与氯化镉对mcf-7细胞增殖及wisp-2和bcl-2蛋白表达作用-effects of bisphenol a and cadmium chloride on proliferation and expression of wisp - 2 and bcl - 2 proteins in mcf - 7 cells
万方数据
万方数据
结论:
1、BPA、CdCl2 单独作用下在一定浓度下能促进 MCF-7 细胞增殖,两 者单独作用对细胞增殖促进作用高于两者联合作用。
2、BPA 能促进 WISP-2 基因的表达,WISP-2 基因能调控 Bcl-2 基因的表 达。
3、BPA 与 CdCl2 联合作用于 MCF-7 细胞时,在一定浓度下,WISP-2 基因和 Bcl-2 基因的表达均低于两者单独作用。
关键词: MCF-7, BPA,CdCl2,WISP-2,Bcl-2,增殖,联合作用
2
Effect of Bisphenol A and CdCl_2 on the viability of MCF-7cells and the protein expression of WISP-2 and Bcl-2
Abstract
Objective: Cell culture was used to investigate and explain the combined effect of bisphenol A and cadmium chloride on the proliferation of MCF-7human breast cancer cells and whether BPA promote the expression of WISP-2 and control BCL-2
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