循证医学与药物流行病学原则在美国fda药物风险评估中应用课件.pptVIP

Life-Table Approach - Focus on Each Interval寿命表法 - 关注每个区间 Drug Risk Assessment - Three Key Questions药物风险评估的三个中心问题 Is a medical event of interest drug-related? (因果关系) What is the magnitude of risk? (风险的大小程度) How can the risk be modified? (如何减少风险) Summary: Three Key Questions in Risk Assessment总结：药物风险评估的三个中心问题 Is a medical event of interest drug-related? (因果关系) What is the magnitude of risk? (风险的大小程度) How can the risk be modified? (如何减少风险) Individual vs. Population 个体与群体的关系 Frequency vs. Incidence Rate 百分比与发生率的关系 Risk Factor vs. Interaction 危险因素与相互作用的关系 Topics that are not covered – what af