抗心律失常药物的离子流机制和临床应用进展课件(英文).pptVIP

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抗心律失常药物的离子流机制和临床应用进展课件(英文).ppt

抗心律失常药物的离子流机制和临床应用进展课件(英文)

抗心律失常药物的离子流机制 和临床应用进展;Case 1 (病例1) ;Question for Case 1 (病例1) ;Question;Basic Electrophysiology;Na+;I;Major Ionic Currents in Ventricular Action Potential;The States of Voltage-Dependent Ionic Channel;Relationship between Volatge-dependent Ion Channel Statuses and Action Potential;INa-mediated action potentials (钠通道介导的动作电位, resting membrane potential -70 mV): fast phase 0 upstroke and conduction velocity that is suppressed by INa blockers. Atria, His-Purkinje conduction tissues, ventricles, accessory pathways; ICa,L-mediated action potentials (钙通道介导的动作电位, resting membrane potential -60 mV

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