器官移植护理课件.pptVIP

*Maintain therapy 1.calcineurin inhibitors cyclosporine(sandimmune1983)(neoral 1995)環孢靈 : block T-helper lymphocyte FK506(Tacrolimus1994) 2.corticosteroids prednisolone Methylprednisolone (solu-medrol) 3.Antimetabolites Cellcept (mycophenolate mofetil 1995) Immuran (azathioprine) 4.TOR (target of rapamycin)inhibitors Rapamune斥消靈 Cyclosporine(CSA)(sandimmune, neoral) Binding to immnophilins cyclophilin and inhibits gerneration of IL2 always take at 8Am and 8Pm (q 12 hrs) side effects: 血壓升高、尿量減少、毛髮增生、牙齦腫脹、手顫抖、頭痛、 (腸胃不適)、腎毒性、高脂血症 每日5-10mg/kg (因人而異), 以肝腎功能及血中治療濃度來調整劑量 避免與葡萄柚同吃, 因會干擾肝