雾化吸入抗生素治疗呼吸机相关感染课件.pptxVIP

Ventilator-associated infection: the role for inhaled antibioticsLucy B. PalmerCurrent opinion in pulmonary medicine 2015, 21:239–249outlineIntroductionPathophysiology and rationaleClinical trialsDrug resistanceConclusionIntroductionVentilator-associated pneumonia (VAP) Ventilator-associated tracheobronchitis (VAT) multidrug resistant (MDR) extensively drug-resistant (XDR) inhaled antibioticsnebulizersPathophysiology and rationaleSubglottic secretions，disturbed mucociliary clearance,damaged mucosa, bacterial biofilm. Pathophysiology and rationaleClinical trials7.8.9.10.11.12.Clinical trials多