人SR-PSOX2fCXCL16基因转染和沉默及其对动脉粥样硬化相关功能的影响.pdfVIP

ABSTRACT Background Atherosclerosis(AS) is a multi-factor-induced chronic disease. Recent studies demonstrated that chemokine and its receptor are involved in the pathogenesis and development of many cardiovascular diseaes,such as AS, myocarditis and cardiomyopathy. It is encouraging to find that inhibition of the immunity of chemokine and its receptor can inhibit the development of AS. SR-PSOX(scavenger receptor that binds phosphatidylserine and oxidized li